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Melatonin has actually been shown to possess anti-inflammatory effects, amongst a number of activities. Melatonin minimizes tissue devastation during inflammatory responses by a number of ways. Thus melatonin, through its capacity to straight scavenge hazardous totally free radicals, decreases macromolecular damage in all organs. The free radicals and reactive oxygen and also nitrogen types known to be fed on by melatonin include the extremely toxic hydroxyl radical, peroxynitrite anion, and also hypochlorous acid, among others. These agents all contribute to the inflammatory reaction and also linked tissue damage. Furthermore, melatonin has various other methods to decrease the damages arising from inflammation.
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